Immunological basis of chlamydia induced reactive arthritis

Immunological basis of Chlamydia induced reactive arthritis.

Introduction A small proportion of patients who present with clinical symptoms of urethritis or cervicitis later develop inflammatory arthritis and, for an unfortunate minority, this can be the beginning of a persistent and disabling disease. This illness is now termed reactive arthritis, rather than the older term, Reiter’s disease. Reiter described a triad of urethritis, conjunctivitis, and a...

Chlamydia-induced reactive arthritis: the potential for eradication

Chlamydia-induced reactive arthritis: hidden in plain sight?

Reactive arthritis belongs to the group of arthritidies known as the spondyloarthritides. There are two main types of reactive arthritis: post-venereal and post-enteric. Chlamydia trachomatis is felt to be the most common cause of reactive arthritis, in general. Until recently, even the terminology for the condition itself was unclear as multiple eponyms and names have been associated with reac...

Persistent infection of Chlamydia in reactive arthritis.

A number of bacteria have been implicated as causing reactive arthritis. In epidemiological studies Chlamydia have been identified as the most common bacteria triggering reactive arthritis in Western countries. Only 1–3% of patients acquiring infection at the urogenital tract as the primary site of infection develop Chlamydia-induced arthritis. It has been shown that C trachomatis reaches the j...

Immunological Basis of Neurological Diseases

Clinical neurology has been traditionally considered as an academic speciality in which the specialist regurgitates his/her knowledge of neurology without being able to do much for the patient. This attitude is no longer acceptable. Surge of information and discoveries in neurosciences within the last two decades translated into therapeutic interventions which is literally life saving in some o...